FCT Funding Projects

Coordination of project funded by Portuguese Foundation

O2Cells

Hybrid living bioengineered hierarchical constructs with self-oxygenating capability

Period: 01-02-2023 – 31-01-2026

Funding Scheme: FCT – 2022.04237.PTDC

Coordination: Prof. João F. Mano – University of Aveiro

Description:

O2Cells intends to be the cutting-edge of a new generation of advanced devices by: (i) exploring natural-based biomaterials for this bottom-up bioengineering process that will combine self-oxygenating microalgae and tissue progenitor cells in original multiscale structural arrangements tuned to stimulate the regeneration of high-quality vascularised microtissue in a symbiotic system; (ii) combine these ingredients in well designed multi-scale devices with precisely tune macro-architectures where cells could freely assemble under the effect of adequate mechanical and biochemical signals.